เอกสารการประชุมวิชาการและเสนอผลงานวิจัย มหาวิทยาลัยทักษิณ ครั้งที่ 19 2552 - page 755

„µ¦ž¦³»¤ª·µ„µ¦Â¨³Áœ°Ÿ¨Šµœª·‹´¥ ¤®µª·š¥µ¨´¥š´„¬·– ‡¦´ÊŠš¸É 19 ž¦³‹Îµže 2552
2
Abstract
Microwave synthesis is eco-friendly synthetic procedure. In this report, microwave synthesis of three
thiocarbamates has been investigated by a reaction of benzoyl chloride, ammonium thiocyanate and alcohols on
the surface of alumina under microwave irradiation using domestic microwave (800 Watts). Methyl N-
benzoylthiocarbamate was obtained in good yield with 10 % power (80 Watts), ten plus five minutes irradiation
and with the mole ratio of starting (benzoyl chloride : ammonium thiocyanate : alcohol) = 1:1:30. Under the same
conditions, ethyl N -benzoylthiocarbamate and isopropyl N -benzoylthiocarbamate were obtained in moderate
yields (52.92 and 55.22%, respectively). The compounds were characterized by NMR (1H and 13C) and FT-IR
spectroscopy techniques. This development of microwave synthesis is a simple procedure for synthesis of
thiocarbamates and a green reaction consuming less organic solvent, time and energy.
Keywords: Thiocarbamates, Microwave synthesis
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