full2010.pdf - page 1322

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°Š‡rž¦³„°šµŠÁ‡¤¸‹µ„Á®Šoµ °Š nµ¨·Š
Chemical Constituents from the Rhizome of Alpinia conchigera Griff
´œ˜· «´„—µ¦´˜œr1 * ¨³ »—µ¦´ ˜œr šœ¡¨„¦´Š 2
Santi Sakdarat and Sudarat Tanphonkrang
š‡´—¥n°
n µ¨·ŠÁž}œ¡ºÄœªŠ«r Zingiberaceae ‹´—Áž}œ¡º¤»œÅ¡¦Åš¥š¸É ¦¼o‹´„¨³œÎµ¤µÄo ž¦³Ã¥œr
„´ œ°¥nµŠÂ¡¦n®¨µ¥ ¤¸ ¦¦¡‡»–˜oµœÁºÊ°Â‡š¸Á¦¸¥ ¦´„¬µÂŸ¨¡»¡°Š ¤¸®œ°Š œ°„‹µ„œ¸Ê¥´Š¤¸
‡» –¤´˜· Áž}œ¥µ‰n µÂ¤¨Š˜nµŠÇ ¨³Á¤ºÉ°œÎµnªœ„´ —‡¨°Ã¦¢°¦r¤ °ŠÁ®Šoµ‹µ„ nµ¨·Š ¤µÂ¥„—oª¥
Áš‡œ·‡Ã‡¦¤µÃš„¦µ¢e¦ª—Á¦Èª µ¤µ¦™Â¥„µ¦ž¦³„°Å—o 3 œ·—µ¦Á®¨nµœ¸Êŗo„n 3,5,7-
trihydroxyflavone (galangin), 3,5,7-trihydroxy-4'-methoxyflavone (kaempferide) ¨³
5,7-dihydroxy-4'-methoxy-3- O-ȕ-D-glucopyranosideflavone (kaempferide-3-O-ȕ-D-
glucoside), š¸É¦· »š›·Í ǦŠ¦oµŠ °Šµ¦¦· »š›·Íš¸ÉÂ¥„Å—oš´ÊŠ 3 œ· —œ¸Ê¡· ¼‹œrš¦µÃ—¥„µ¦Äo
o °¤¼¨šµŠÁž„ڦÇže‹µ„ UV, IR, MS, 1H-NMR ¨³ 13C-NMR, µ¦Á®¨nµœ¸ÊŤn Á‡¥¡Äœ
¡º œ·—œ¸Ê¤µ„n°œ
‡Î µÎµ‡´: nµ¨·Š, Galangin, Kaempferide, Kaempferide-3-O-ȕ-D-glucoside.
Abstract
Alpinia conchigera Griff, a Thai medicinal plant of family Zingiberaceae, is
well-known plant used in Thai traditional medicine as an antibacterial and antiulcer.
Moreover it has insecticidal properties. The chloroform crude extract of the rhizomes
of Alpinia conchigera Griff was purified by column chromatography and preparative
thin-layer chromatography to give three pure compounds. Structural elucidation of the
isolated compounds was carried out on the basis of spectral analyses. Two of these
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1 Asst. Prof. Dr., School of Chemistry, Institute of Science, Suranaree University of Technology,
Nakhon Ratchasima, 30000, Thailand.
* correspondence author E-mail: santi@sut.ac.th
2 Master’s Degree Student, School of Chemistry, Institute of Science, Suranaree University of
Technology, Nakhon Ratchasima, 30000, Thailand.