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Abstract
The aim of this research was to studied the effect of the amount 2-hydroxyethyl methacrylate (2-
HEMA) monomer on properties of hydrogel from mucilage gel of Ocimum canum Sims. by grafting, using
ammonium persulfate as an initiator. The amount of 2-HEMA 0.0900, 0.2707, 0.4507 and 0.6314 mol/l were
studied. The experimental results showed that the amount of 2-HEMA 0.0900 mol/l was suitable for forming
hydrogel sheet and stable during water absorption. The water absorbency of hydrogel in distilled water, various
salt solution and various pH buffer solution were investigated. The results indicated that water absorbency of
hydrogels in distilled water was increased with increasing the amount of 2-HEMA. The tendency of hydrogel
for water absorption in the solution of NaCl, CaCl2 and FeCl3 exhibits in order Na + > Ca2+ > Fe3+. Moreover, the
water absorbency for hydrogel in monovalent cation solutions is in order LiCl >NaCl > KCl. In various pH buffer
solution, the water absorbency of hydrogel change depends on pH values. Thus pH controlled drug delivery is
made possible by developed hydrogel from mucilage gel of Ocimum canum Sims.
Keywords : 2-Hydroxyethyl methacrylate, Ocimum canum Sims., Grafting
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