เอกสารการประชุมวิชาการและเสนอผลงานวิจัย มหาวิทยาลัยทักษิณ ครั้งที่ 19 2552 - page 50

„µ¦ž¦³»¤ª·µ„µ¦Â¨³Áœ°Ÿ¨Šµœª·‹´¥ ¤®µª·š¥µ¨´¥š´„¬·– ‡¦´ÊŠš¸É 19 ž¦³‹Îµže 2552
Abstract
The mangrove forests are important for the natural ecosystems, especially the habitat of juvenile aquatic
animals and a variety of plant species. Some mangrove plants have pharmacological properties, in particular
free radical scavenging and medicinal activity. In this research, one hundred grams of each 8 mangrove species
(16 samples) located at Rajamangala Beach, Trang Province were extracted with methanol. The extracted samples
were assayed for antioxidant activity with DPPH (1,1-diphenyl-2-picrylhydrazyl) radical, total polyphenolic
compounds and flavonoid contents. The antioxidant capacity at the half maximal inhibitory concentration (IC50) of
young Rhizophora mucronata pod extracted was 0.011 mg/ml. This value was higher than standard BHA (0.04
mg/ml) and other plant extracts. The equivalent IC50 values (0.014 mg/ml) were found for Sonneratia caseolaris
leaves and Xylocarpus granatum seed extracts. The maximum value of the total antioxidant was found in S.
caseolaris leaves extract (92.05 mg BHA/g dried plant) and lower in R. mucronata bark and X. granatum seeds
extracts (82.8 and 50.21 mg BHA/g dried plant, respectively) but in young R. mucronata pod, it was
approximately reduce half of S. caseolaris leaves extract. The total polyphenolic compounds and flavonoid
contents were highest in R. mucronata bark at 48.17 mg gallic acid and 31.41 mg catechin/g dried plants,
respectively and followed by S. caseolaris leaves, young R. mucronata pod and X. granatum seeds extracts. The
results suggests the mangrove plants are a good sources of natural antioxidants, polyphenolic and flavonoid
compounds and farther studies should be undertaken for their pharmacological properties.
Keywords: Antioxidant ; Mangroves plants
‡Î µœÎµ
Ĝ·ÉŠ¤¸¸ª·˜š´ÊŠ¡ºÂ¨³´˜ªrš» „œ·—¤¸„¦³ªœ„µ¦‡ª‡»¤°œ»¤¼¨°· ¦³ (antioxidant defense system) Á¡ºÉ°
¦´„¬µ¤—» ¨ °Š°œ»¤¼ ¨°· ¦³£µ¥Äœ¦nµŠ„µ¥ Á¦¸¥„µ¦š¸É šÎµ®œoµš¸ÉĜ„¦³ªœ„µ¦„ε‹´ —°œ»¤¼¨°· ¦³ªnµ µ¦˜oµœ
°°„Ž·Á—´œ (antioxidants) Ž¹É ŠšÎµ®œoµš¸É‡ª‡»¤¤—»¨ °Š°œ» ¤¼¨°· ¦³ Ĝ£µª³š¸É¤¸ž¦·¤µ–°œ»¤¼¨°· ¦³¤µ„„ªnµš¸É
¦³žj°Š„´œ‹³¥´¥´Ê Š°œ»¤¼¨—´Š„¨nµªÅ—ošÎ µÄ®oÁ„·—£µª³ oxidative stress nŠŸ¨Ä®o °œ»¤¼¨°· ¦³ÅžšÎ µ¨µ¥ÁœºÊ°Á¥ºÉ°Â¨³
°ª´ ¥ª³˜nµŠ Ç °Š¦nµŠ„µ¥nŠŸ¨Ä®oÁ„·—¡¥µ›· £µ¡Å—o (Ames ¨³‡–³, 1993)
„µ¦Å—o ¦´µ¦˜oµœ°œ» ¤¼¨°· ¦³‹µ„£µ¥œ°„°µ‹‹³Áž} œž{‹‹´ ¥Îµ‡´ š¸Énª¥nŠÁ¦·¤„µ¦‡ª‡»¤Â¨³„µ¦
žj °Š„´œ°´œ˜¦µ¥‹µ„°œ»¤¼¨°· ¦³š¸ÉÁ„· — ¹Êœ ˜n µ¦˜oµœ°œ»¤¼¨°· ¦³š¸É ™¼„´ŠÁ‡¦µ³®r¹Êœ‹µ„„¦³ªœ„µ¦šµŠÁ‡¤¸‹³¤¸
o°‹Î µ„´—Äœ„µ¦Äo ŠµœÂ¨³‡ªµ¤ž¨°—£´¥Äœ„µ¦¦·Ã£‡šÎ µÄ®o¤¸ „µ¦«¹„¬µµ¦°°„§š›·Í ˜oµœ°œ»¤¼¨°· ¦³‹µ„
›¦¦¤µ˜·¤µ„ ¹ÊœÄœž{‹‹» ´œÃ—¥ÁŒ¡µ³µ¦˜oµœ°œ» ¤¼¨°· ¦³‹µ„¡ºÂ¨³¤»œÅ¡¦Åš¥ Ž¹ÉŠµ¤µ¦™œÎµž¦³¥»„˜r čo
ĜšµŠÁ£´ ª·š¥µ „µ¦Â¡š¥r Ÿ¨·˜£´–”rÁ¦·¤‡ªµ¤Šµ¤®¦º°Á‡¦ºÉ °ŠÎµ°µŠ ¨³°»˜µ®„¦¦¤°µ®µ¦ Á¡ºÉ°¨—„µ¦œÎµÁ oµ
µ¦´ŠÁ‡¦µ³®r‹µ„˜nµŠž¦³Áš« °¸„š´ÊŠÁž} œ„µ¦nŠÁ¦·¤Â¨³Á¡·É¤¤¼¨‡n µÄ®o„´š¦´¡¥µ„¦›¦¦¤µ˜·°ŠÅš¥š¸É¤¸‡ªµ¤
®¨µ„®¨µ¥šµŠ¸ª£µ¡Â¨³nª¥nŠÁ¦· ¤£¼¤·ž{µµªo µœÄ®očo¡º ¤»œÅ¡¦Åš¥°¥n µŠ™¼„ª·›¸Â¨³¤¸ ‡ªµ¤ž¨°—£´¥
×¥ÁŒ¡µ³µ¦„´—‹µ„¡º¡ºÊ œ™·ÉœŽ¹ÉŠÅ—o¦´‡ªµ¤œÄ‹Áž}œ°¥nµŠ¤µ„Á¡¦µ³®µÅ—oŠnµ¥ ÁnœÁ—¸ ¥ª„´¡ºÊœš¸É°¥¼n £µ¥Äœ‡–³