1323
P89
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Effects of Tetracycline Rice Gel on Bacteria in Periodontal Pockets
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Jaruporn Limtragool
1*
, Sakornrat Khongkhunthian
2
,ǰPattanin Montreekachon
3
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and Siriporn Okonoki
4
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Abstract
Aim of this study was to evaluate effect of tetracycline rice gel on the reduction of total
bacteria and
Porphyromonas gingivalis
XJUIJOǰEFFQǰQFSJPEPOUBMǰQPDLFUTǰ œǰ ǰNN ǰPGǰ ǰQBUJFOUTǰXJUIǰ
chronic periodontitis. In each patient, 1 periodontal pocket was selected to be a control site, applying
with a base rice gel, whereas 40% (weight/volume) tetracycline rice gel was applied in other
periodontal pockets. Subgingival plaque sample was collected before the gel placement and also 1
hour, 3 hours, 1 day, and 3 days after the application. Bacterial analysis is performed by real-time PCR.
Results showed significant differences in the reduction of both total bacteria and
P. gingivalis
between
control and tetracycline groups on the 3
rd
day. It was concluded that developed rice gel has
effectiveness on bacterial reduction in periodontal pockets. Rice gel could be used as local drug
delivery in oral cavity.
Keywords:
Local Drug Delivery, Tetracycline Rice Gel
,
Chronic Periodontitis,
Porphyromonas gingivalis
1
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÷ÜĔĀöŠ
50200
2
ñý ìóâ éø , õćÙüĉ
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3
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4
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ǰ50200
*Corresponding author: Tel.: 081-5463425. E-mail address:
