1042
P50
ùìíĉĝ
êš
ćîĂĂÖàĉ
đéßĆ
îĒúąùìíĉĝ
÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿ×ĂÜĔïǰÖĉę
ÜǰĒúąđðúČ
ĂÖñú×ĂÜÝĞ
ćðćéą
Antioxidant and Antityrosinase Activities of Leaves, Brances and Peels of
Artocarpus integer
üøøèùéĊ
Āĉ
øĆ
âøĆ
êîŤ
1*
ĒúąĂĆ
þãćüč
í Āĉ
øĆ
âøĆ
êîŤ
1
Wanrudee Hiranrat
1*
and Asadhawut Hiranrat
1
ïìÙĆ
é÷Š
Ă
Üćîüĉ
ÝĆ
÷îĊĚ
đðŨ
îÖćøýċ
Öþćùìíĉĝ
êš
ćîĂĂÖàĉ
đéßĆ
î Ēúąùìíĉĝ
÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿ ×ĂÜÿćøÿÖĆ
éđĂìćîĂúÝćÖĔï Öĉę
Ü
ĒúąđðúČ
ĂÖñú×ĂÜÝĞ
ćðćéą
îĞ
ćĔï Öĉę
Ü ĒúąđðúČ
ĂÖñú×ĂÜÝĞ
ćðćéąìĊę
ĒĀš
ÜöćÿÖĆ
ééš
ü÷đĂìćîĂúìĊę
Ăč
èĀõĎ
öĉ
Āš
ĂÜĕéš
ÿćøÿÖĆ
é EEL
EEB Ēúą EEP êćöúĞ
ćéĆ
ï ìéÿĂïùìíĉĝ
êš
ćîĂĂÖàĉ
đéßĆ
îéš
ü÷üĉ
íĊ
1,1-diphenyl-2-picrylhydrazyl (DPPH) assay ēé÷Ĕßš
BHT
(butylated hydroxytoluene) đðŨ
îÿćøÙüïÙč
öĒïïïüÖ ĒúąìéÿĂïùìíĉĝ
÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿ éš
ü÷üĉ
íĊ
dopachrome
Ĕßš
L-DOPA đðŨ
îÿćøêĆĚ
Üêš
î ÖøéēÙÝĉ
ÖđðŨ
îÿćøÙüïÙč
öĒïïïüÖ
ñúÖćøìéúĂÜóïüŠ
ć EEB ĒÿéÜùìíĉĝ
êš
ćîĂĂÖàĉ
đéßĆ
î IC
50
=
25.12±1.
17
P
g/ml Ēúąùìíĉĝ
÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿ IC
50
=
0.11±0.03
P
g/ml ÿĎ
ÜìĊę
ÿč
é ÿŠ
üî BHT ĒúąÖøéēÙÝĉ
Öàċę
ÜđðŨ
î
ÿćøÙüïÙč
öĒïïïüÖöĊ
ÙŠ
ć IC
50
=
21.73±1.
12 Ēúą
0.04±0.0
2
P
g/ml êćöúĞ
ćéĆ
ï øĂÜúÜöćÿćøÿÖĆ
éìĊę
ĒÿéÜùìíĉĝ
êš
ćî
ĂĂÖàĉ
đéßĆ
îĒúąùìíĉĝ
÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿÙČ
Ă EEL Ēúą EEP êćöúĞ
ćéĆ
ï ÝćÖÜćîüĉ
ÝĆ
÷îĊĚ
ĒÿéÜüŠ
ćÿćøÿÖĆ
éđöìćîĂúÝćÖÖĉę
Ü×ĂÜ
ÝĞ
ćðćéąÿćöćøëđðŨ
îĒĀúŠ
Ü×ĂÜÿćøêš
ćîĂĂÖàĉ
đéßĆ
îĒúą÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿìĊę
éĊ
ĕéš
ÙĞ
ćÿĞ
ćÙĆ
âǰ :
ùìíĉĝ
êš
ćîĂĂÖàĉ
đéßĆ
î ùìíĉĝ
÷Ć
ï÷ĆĚ
ÜđĂîĕàöŤ
ĕìēøàĉ
đîÿ ÝĞ
ćðćéą
Abstract
The antioxidant and antityrosinase activities of the ethanolic extracts of leaves, branches and
peels of
Artocarpus integer
were investigated. Samples were harvested at
Amphoe Khuan Khanun
,
Phatthalung Province.
The dried powder of leaves, branches and peels was extracted at room
temperature with ethanol to give the EEL, EEB and EEP crude extracts, respectively.The antioxidant activity
was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, using butylated hydroxytoluene (BHT) as a
standard. Tyrosinase inhibitory activity was measured using the modified dopachrome method with L-
DOPA as a substrate and kojic acid as standard. The results showed that the antioxidant and
antityrosinase activities were found to be highest in the EEB extract
IC
50
=
25.12±1.
17
P
g/ml and IC
50
=
0.11±0.03
P
g/ml,
respectively) followed by the EEL and EEP crude extracts, respectively. The results of
this study proved that the ethanolic extract of branches can be excellent sources of antioxidant and
antityrosinase compounds.
Keywords :
Antioxidant activity, Antityrosinase activity,
Artocarpus integer
1
Ă., ÿć×ćüĉ
ßćđÙöĊ
Ùèąüĉ
ì÷ćýćÿêøŤ
öĀćüĉ
ì÷ćúĆ
÷ìĆ
Öþĉ
è óĆ
ìúč
Ü 210
*
Corresponding author : Tel. 098-1595162E-mail address :
