1090
P57
ÖćøêøüÝüĉ
đÙøćąĀŤ
ÖćøðúĂöðî÷ćĒñîðŦ
ÝÝč
ïĆ
îĔî÷ćĒñîĕì÷Ĕîđ×êÝĆ
ÜĀüĆ
éÿÜ×úć
Determination of eight-adulterated drugs in Thai herbal medicines
in Songkhla Province
èüÜýŤ
ǰïč
îîćÙ
1
÷Ü÷č
ìíŤ
ǰđìóøĆ
êîŤ
2
ǰßúìĉ
êǰÿîíĉ
đöČ
ĂÜ
3
ǰĒúąÿč
ßćéćǰÝĆ
îìøŤ
óøĀööć
4
Nawong Boonnak
1
, Yongyuth Theapparat
2
Chonlatid Sontimuang
3
and Suchada Chantrapromma
4
ïìÙĆ
é÷Š
Ă
Üćîüĉ
ÝĆ
÷îĊĚ
đðŨ
îÖćøüĉ
đÙøćąĀŤ
ÖćøðúĂöðî÷ćĒñîðŦ
ÝÝč
ïĆ
îĔî÷ćĒñîĕì÷×ĂÜñĎš
ñúĉ
ê÷ćÿöč
îĕóøđóČę
ĂîĞ
ćך
ĂöĎ
úöćĔßš
ðøąđöĉ
îÙüćöđÿĊę
÷Ü×ĂÜðøąßćßîìĊę
Ýąĕéš
øĆ
ï÷ćĒñîĕì÷ìĊę
ĕöŠ
ĕéš
öćêøåćî ēé÷ÖćøÿčŠ
öđÖĘ
ïêĆ
üĂ÷Š
ćÜ÷ćĒñîĕì÷ÝĞ
ćîüî 207
êĆ
üĂ÷Š
ćÜ ÝćÖĒĀúŠ
ÜÝĞ
ćĀîŠ
ć÷ìĆĚ
ÜÿĉĚ
î 48 ĒĀŠ
Ü ĔîóČĚ
îìĊę
ÝĆ
ÜĀüĆ
éÿÜ×úć ÷ćĒñîĕì÷êĆ
üĂ÷Š
ćÜëĎ
ÖêøüÝÿĂïÖćøðúĂöðî÷ćđïČĚ
ĂÜêš
î
éš
ü÷đìÙîĉ
ÙēÙøöćēìÖøćôŘ
ĒñŠ
îïćÜđìĊ
÷ïÖĆ
ï÷ćöćêøåćîĔîøąïïêĆ
üßąìĊę
đĀöćąÿö óïÖćøðúĂöðîÿćøÿš
öÝĞ
ćîüî 1 êĆ
üĂ÷Š
ćÜ
Ùĉ
éđðŨ
îøš
Ă÷úą 0.48 ĒúąÖćøðúĂöðî×ĂÜ÷ć acetaminophen ÝĞ
ćîüî 6 êĆ
üĂ÷Š
ćÜ Ùĉ
éđðŨ
îøš
Ă÷úą 2.90 ĒúąìĞ
ćÖćø
üĉ
đÙøćąĀŤ
đßĉ
ÜÙč
èõćó×ĂÜ÷ćéĆ
ÜÖúŠ
ćüēé÷Ĕßš
đìÙîĉ
ÙēÙøöćēìÖøćôŘ
×ĂÜđĀúüÿöøøëîąÿĎ
Ü÷Č
î÷Ć
îÖćøðúĂöðî÷ćĂąđàêćöĉ
ēîđôî
ÙĞ
ćÿĞ
ćÙĆ
â
: ÖćøðúĂöðî÷ćĒñîðŦ
ÝÝč
ïĆ
î ÷ćĒñîĕì÷ ÿćøÿš
ö ÷ćĂąđàêćöĉ
ēîđôî
Abstract
The purpose of this research is to determine adulterated drugs in Thai herbal medicines for the
risk evaluation of people who take those medicines. Two hundred seven samples of Thai herbal
medicines were collected randomly from 48 drug stores in Songkhla province. All drug samples were
determined for drug adulterant by using thin-layer chromatography (TLC) technique, and compared with
standard drugs. The results showed that one sample was adulterated with alum, calculated as 0.48%, 7
samples were adulterated with acetaminophen, calculated as 2.90%. Moreover, the quanlity of the
adulterant in the latter samples was further determined by HPLC, the result showed remarkable amounts
of acetaminophen in the crude drug.
Keywords
: Drug adulterants, Thai herbal medicine, Alum, Acetaminophen
1
éø., ÿć×ćüĉ
ßćđÙöĊ
Ùèąüĉ
ì÷ćýćÿêøŤ
öĀćüĉ
ì÷ćúĆ
÷ìĆ
Öþĉ
è óĆ
ìúč
Ü 93110
2
éø , ÙèąÿĆ
êüĒóì÷ýćÿêøŤ
öĀćüĉ
ì÷ćúĆ
÷đìÙēîēú÷Ċ
øćßöÜÙúýøĊ
üĉ
ßĆ
÷ üĉ
ì÷ćđ×êîÙøýøĊ
íøøöøćß
3
éø , ÙèąÖćøĒóì÷Ť
Ēñîĕì÷ öĀćüĉ
ì÷ćúĆ
÷ÿÜ×úćîÙøĉ
îìøŤ
üĉ
ì÷ćđ×êĀćéĔĀâŠ
90110
4
øý éø , õćÙüĉ
ßćđÙöĊ
Ùèąüĉ
ì÷ćýćÿêøŤ
öĀćüĉ
ì÷ćúĆ
÷ÿÜ×úćîÙøĉ
îìøŤ
üĉ
ì÷ćđ×êĀćéĔĀâŠ
90110
Corresponding author: Tel.: 074-693995. E-mail address:
