1382
Throughout the study, compliance was good that each subject was able to follow protocol at
more than 75%. Statistical analysis also revealed that there were no significant differences in drug uses
between groups (Chi-square tests) throughout the study too although some patients in both groups
had changes theirs drugs.
Table 3 showed comparison of the biochemical parameters between WR and SYBR group during
24 weeks of dietary intervention. Although, both groups had no significant change of fasting plasma
glucose but their mean value of HbA1c gradually decreased from wk0. Only SYBR group had mean
HbA1c at wk24 significantly less than both wk8 and wk16. It was found that mean value of serum
insulin of SYBR group was significantly increased at wk8, however its means at wk16 and wk24 were not
significantly different from wk0 but no significant changes were shown in WR group during 24 weeks.
Results indicated that subjects whose consumed Sangyod brown rice at least 2 meals/day had
better glucose control according to the results of HbA1c than subjects consumed white rice. Nutrient
analysis showed that SYBR group had significantly higher dietary fiber intake, approximately 3.8 g/d
than WR group which came from average 267 g/d of cooked Sangyod brown rice during 24-wk dietary
intervention. Since there were no significant differences in total energy, protein, fat, carbohydrate and
dietary fiber from other sources and also anthropometric measurements between two groups.
Table3
Comparison of the biochemical parameters between WR (n = 36) and SYBR (n = 36) group at
each visit. Data were expressed as means (SD)
Parameters
Group
Wk0
Wk8
Wk16
Wk24
FBG (mg/dL)
WR
153 (52)
145 (54)
147 (55)
148 (59)
SYBR
142 (43)
135 (41)
141 (54)
133 (39)
HbA1c (%)*
WR
8.0 (1.5)
7.6
(1.4)
†
7.5 (1.4)
†
7.3 (1.4)
†
SYBR
7.9 (1.6)
7.5 (1.2)
†
7.4 (1.4)
†
7.2 (1.4)
†‡
Insulin (μIU/ml)
WR
SYBR
4.9 (2.1)
5.9 (2.3)
5.2 (2.1)
7.2 (2.2)
†
5.4 (2.0)
6.7 (2.2)
4.5 (2.1)
5.5 (2.4)
*
Nonparametric test with Friedman test, followed Wilcoxon Sign Rank test was used, p <0.05
Significantly different from
†
wk0 and
‡
both wk8 and wk16 within the same group.
The favorable effects of Sangyod brown rice in this study could be explained by several
mechanisms. Among them, dietary fiber may be the most important factor that had been known to
control blood glucose concentrations. Sangyod brown rice rich in dietary fiber, 4.1 g/100 g may be
