7
ก M @:
M ก Q; E;A =@:
F
EMp UV
><H=IJ
C = @
;9:
K =@:
>! MR
?! @
=@:
E
ก กG C G (
L.
plantarum
TISTR 050)
9:
; @
ก F
@
E
> Q EM>
L.
plantarum
TISTR 050 C
G G transformants =@:
@
ก ? ;;กQ; @
E
? H=IJ
M. luteus
TISTR 884 E??@
ก C G ; C
9:
; C ก MR
H=IJ
ก < ก ? ; E E
=@:
transformants p ;;ก
L ; E [polymer
Q; N-agetylglucosamine (NAG) !9:
; ก ? I Eก A ? =@:
F
<
β
-1,4) (Bokma
et al.
, 1997) D:
@
; M ก;G=@:
D
กG pepdidoglycan [polymer Q; NAG กG N-acetylmuramic acid (NAM) !9:
; ก ? I
Eก A ? =@:
F
<
β
-1,4)] =@:
MR
M ก;GQ; A
p
Q; G =@
@
(Gee , 2534; Alakomi
et
al.
, 2000) =@:
Lq
ก=F
E?? ; E lysozyme
9:
; C ก ; E =B
2 ! ? L=F
I Eก A ? E?
! ?@
ก =B
LLq
ก!ก F
>< @
ก p :
q
QDB
9:
; @
E E A
peptidoglycan p ; q
>
; < @B
!9B
; (Bernasconi
et al.
, 1986)
R ก
E;A
G =@
@
ก=@:
กE?C ก; < ? H=IJ
C = @
;9:
K =@:
>! MR
?! @
E?E ?@
9:
; @B
> ; <
@B
!9B
; Qy
TS
9:
;M G pH Q; BF
@B
!9B
;>< MR
ก ก; F
EM=? ;G
? H=IJ
C = @
?! @
C
MR
H=IJ
Q; ก ?
ก <y
E? BF
@B
!9B
;=@:
E E?M G pH ;;กH=IJ
G =@
@
ก G กE??@
ก G =@
@
ก G ;กC ก @B
BF
@B
!9B
;Q;
Lactobacillus plantarum
TISTR 050 =@:
@
ก p ; E E
;;กH=IJ
Micrococcus luteus
TISTR 884 E??@
ก C = @
?! @
;9:
K C ก C B
@B
C @
M A ! > ก ? 9
;ก
E;A Q; G =@
@
ก
= M GM
I; <
9:
; v >! MR
AM EGA; ก =@:
@
M =IP ;EM> ;
D
W
C E? G= G C ก F
ก ก; = G ก C (RSA5080008)
= G G
C ก < = ก (WU-51109) Q;Q;G F
ก ! < !
I Q < =
ก =@:
>< ;
< L =@:
9:
; 9
;> ก =F
C
ก
! = M =IJ
Pq
M @
! C = ?@
A L@
กC
กq
.(2545).
G =; A; Q; !9B
;
Lactobacillus
spp. =@:
กE?C ก; < .
$ ก J.
. J
$ .
4(2), 10-20.
Gee Q @
. 2534.
$
'
.
B
=@:
3. ก = : F
ก A; ?@
A .
M !
QC
ก?J
! ก A P .(2542). ก ? 9
;ก !9B
;
; ? G =@
@
=@:
G =; A;
C ก; < < ก.
ก ! ก S ! D
B.
11(2), 65-71.
M !
QC
ก?J
! ก A P .(2543).
; ? G =@
@
:
G B
ก C e ; !9B
;C = @
.
ก ! ก S ! D
B.
12(3), 101-107.
